Structured Summary
Abstract
An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H25NO5
- Molecular Weight
- 371.4 g/mol
- CAS Registry No.
- 102491-77-0
- IUPAC Name
- 1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one
- InChIKey
- NNJPGOLRFBJNIW-UHFFFAOYSA-N
- SMILES
- CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
- MeSH Unique ID
- D003703
- Source
- PubChem CID 2832
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Colchamine
- Colcemid
- Colcemide
- Demecolcine, (+-)-Isomer
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
/biosyn permitted if by plant
MeSH Record
History Note
73(72)
MeSH Record
Previous Indexing
- Alkaloids (1966-1971)
- Antineoplastic Agents (1966-1971)
- Colchicine (1966-1971)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Demecolcine. Medical Subject Headings (MeSH). 2026. Unique ID D003703. http://id.nlm.nih.gov/mesh/2026/D003703
- Demecolcine. In: Wikidata. https://www.wikidata.org/wiki/Q16959658
- Demecolcine. In: PubChem Compound. CID 2832. https://pubchem.ncbi.nlm.nih.gov/compound/2832