Chemicals and Drugs

Cyclin-Dependent Kinase Inhibitor p57

A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expression of p57 is associated with various NEOPLASMS as well as with BECKWITH-WIEDEMANN SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expression of p57 is associated with various NEOPLASMS as well as with BECKWITH-WIEDEMANN SYNDROME.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • CDKN1C Protein
  • Cyclin Kinase Inhibitor Protein 2
  • Cyclin-Dependent Kinase Inhibitor 1C
  • p57 KIP2 Protein
  • p57KIP2 Protein
  • Cyclin Dependent Kinase Inhibitor 1C
  • Cyclin Dependent Kinase Inhibitor p57
  • KIP2 Protein, p57

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1995)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.225w.700
  2. D12.776w.167.187w.700
  3. D12.776w.476.225w.700
  4. D12.776w.624.776.355w.700

AMA Style

References

  1. National Library of Medicine. Cyclin-Dependent Kinase Inhibitor p57. Medical Subject Headings (MeSH). 2026. Unique ID D050761. http://id.nlm.nih.gov/mesh/2026/D050761
  2. Cyclin-Dependent Kinase Inhibitor p57. In: Wikidata. https://www.wikidata.org/wiki/Q5198257