Structured Summary
Abstract
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.
MeSH Record
Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
16 entry terms
- CDK2-Associated Protein 20 kDa
- CDKN1 Protein
- CDKN1A Protein
- Cdk-Interacting Protein 1
- Cdk2 Inhibitor Protein
- Cell Cycle Regulator p21
- Cyclin Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor 1A Protein
- Senescent Cell-Derived Inhibitor Protein 1
- p21 Cell Cycle Regulator
- p21 Cyclin Kinase Inhibitor
- CDK2 Associated Protein 20 kDa
- Cdk Interacting Protein 1
- Cyclin Dependent Kinase Inhibitor 1A Protein
- Cyclin Dependent Kinase Inhibitor p21
- Senescent Cell Derived Inhibitor Protein 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1993)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cyclin-Dependent Kinase Inhibitor p21. Medical Subject Headings (MeSH). 2026. Unique ID D050759. http://id.nlm.nih.gov/mesh/2026/D050759
- Cyclin-Dependent Kinase Inhibitor p21. In: Wikidata. https://www.wikidata.org/wiki/Q24768795