Chemicals and Drugs

Complement C4a

The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • C4a Complement
  • Complement 4a
  • Complement Component 4a
  • C4a, Complement
  • Complement, C4a
  • Component 4a, Complement

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1990)

MeSH Record

Previous Indexing

  • Anaphylatoxins (1980-1982)
  • Complement 4 (1978-1989)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Complement C4a. Medical Subject Headings (MeSH). 2026. Unique ID D015934. http://id.nlm.nih.gov/mesh/2026/D015934
  2. Complement C4a. In: Wikidata. https://www.wikidata.org/wiki/Q21102477