Structured Summary
Abstract
A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Binding of collectins to microorganisms results in their agglutination and enhanced clearance. Collectins form trimers that may assemble into larger oligomers. Each collectin polypeptide chain consists of four regions: a relatively short N-terminal region, a collagen-like region, an alpha-helical coiled-coil region, and carbohydrate-binding region.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
3 entry terms
- Collagenous Lectins
- Collectin
- Lectins, Collagenous
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; use COLLECTINS (NM) 1980-2002
MeSH Record
Previous Indexing
- Carrier Proteins (1980-2002)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QW 640
AMA Style
References
- National Library of Medicine. Collectins. Medical Subject Headings (MeSH). 2026. Unique ID D037222. http://id.nlm.nih.gov/mesh/2026/D037222
- Collectins. In: Wikipedia. https://en.wikipedia.org/wiki/Collectin
- Collectins. In: Wikidata. https://www.wikidata.org/wiki/Q83167205