Structured Summary
Abstract
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
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Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
10 entry terms
- Apoptotic Protease Activating Factor 3
- Caspase-9
- ICE-LAP6 Protein
- ICE-Like Apoptotic Protease 6
- ICE LAP6 Protein
- ICE Like Apoptotic Protease 6
- Pro-Caspase-9
- Procaspase-9
- Pro Caspase 9
- Procaspase 9
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9
MeSH Record
History Note
2007(2005)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Caspase 9. Medical Subject Headings (MeSH). 2026. Unique ID D053453. http://id.nlm.nih.gov/mesh/2026/D053453
- Caspase 9. In: Wikidata. https://www.wikidata.org/wiki/Q24779678