Chemicals and Drugs

Carbenoxolone

An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.

Chemical Identity

Chemical Information

Molecular Formula
C34H50O7
Molecular Weight
570.8 g/mol
CAS Registry No.
5697-56-3
IUPAC Name
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
InChIKey
OBZHEBDUNPOCJG-WBXJDKIVSA-N
SMILES
C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)OC(=O)CCC(=O)O)C)(C)C(=O)O
MeSH Unique ID
D002229
Source
PubChem CID 636403

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

20 entry terms
  • Carbeneoxolone
  • Carbenoxalone
  • 18alpha-Carbenoxolone
  • 18alpha-Glycyrrhetinic Acid 3beta-O-Hemisuccinate
  • Biogastrone
  • Bioral
  • Carbenoxolone Disodium Salt
  • Carbenoxolone Sodium
  • Carbosan
  • Duogastrone
  • Glycyrrhetinic Acid 3-O-hemisuccinate
  • Pharmaxolon
  • Sanodin
  • 18alpha Carbenoxolone
  • 18alpha Glycyrrhetinic Acid 3beta O Hemisuccinate
  • 3-O-hemisuccinate, Glycyrrhetinic Acid
  • 3beta-O-Hemisuccinate, 18alpha-Glycyrrhetinic Acid
  • Acid 3-O-hemisuccinate, Glycyrrhetinic
  • Acid 3beta-O-Hemisuccinate, 18alpha-Glycyrrhetinic
  • Glycyrrhetinic Acid 3 O hemisuccinate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn permitted if by plant

MeSH Record

History Note

1991(1975); for 18ALPHA-CARBENOXOLONE use CARBENOXOLONE (NM) 1995-2002

MeSH Record

Previous Indexing

  • Glycyrrhiza (1966-1974)
  • Succinates (1974)
  • Triterpenes (1974)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 66

AMA Style

References

  1. National Library of Medicine. Carbenoxolone. Medical Subject Headings (MeSH). 2026. Unique ID D002229. http://id.nlm.nih.gov/mesh/2026/D002229
  2. Carbenoxolone. In: Wikipedia. https://en.wikipedia.org/wiki/Carbenoxolone
  3. Carbenoxolone. In: Wikidata. https://www.wikidata.org/wiki/Q752861
  4. Carbenoxolone. In: PubChem Compound. CID 636403. https://pubchem.ncbi.nlm.nih.gov/compound/636403