Chemicals and Drugs

Camphor 5-Monooxygenase

A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site.

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Classification

Broader headings

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MeSH Record

Synonyms

10 entry terms
  • CYP101
  • Camphor-5-Monooxygenase
  • Cytochrome P-450 101
  • Cytochrome P-450(cam)
  • Cytochrome P-450-cam
  • Cytochrome P450(cam)
  • P450cam
  • Camphor 5 Monooxygenase
  • Cytochrome P 450 101
  • Cytochrome P 450 cam

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

97; was CAMPHOR-5-MONOOXYGENASE (NM) 1973-96

MeSH Record

Previous Indexing

  • Camphor (1973-1982)
  • Cytochrome P-450 (1973-1996)
  • Hydroxylases (1973-1996)

MeSH Hierarchy

Tree Numbers

  1. D08.244w.453w.012w
  2. D08.811w.682w.690w.708.170w.012w
  3. D12.776w.422w.220w.453w.012w

AMA Style

References

  1. National Library of Medicine. Camphor 5-Monooxygenase. Medical Subject Headings (MeSH). 2026. Unique ID D019475. http://id.nlm.nih.gov/mesh/2026/D019475
  2. Camphor 5-Monooxygenase. In: Wikipedia. https://en.wikipedia.org/wiki/Camphor_5-monooxygenase
  3. Camphor 5-Monooxygenase. In: Wikidata. https://www.wikidata.org/wiki/Q3655330