Chemicals and Drugs

CD48 Antigen

A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

21 entry terms
  • B-Lymphocyte Activation Marker BLAST-1
  • BCM1 Surface Antigen
  • Blast1 Antigen
  • Leukocyte Antigen MEM-102
  • MRC OX-45 Antigen
  • P41 Antigen
  • SLAM Family Member 2
  • SLAMF2 Protein
  • Signal-Transducing Glycoprotein-60
  • Signaling Lymphocytic Activation Molecule 2
  • Signaling Lymphocytic Activation Molecule Family Member 2
  • Antigen, CD48
  • Antigen, MRC OX-45
  • Antigen, P41
  • B Lymphocyte Activation Marker BLAST 1
  • Glycoprotein-60, Signal-Transducing
  • Leukocyte Antigen MEM 102
  • MEM-102, Leukocyte Antigen
  • MRC OX 45 Antigen
  • Signal Transducing Glycoprotein 60
  • Surface Antigen, BCM1

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017 (1990)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.448.180w
  2. D09w.400w.430w.890w.736w.250w
  3. D12.776w.395w.550w.448.180w
  4. D12.776w.395w.550w.736w.250w
  5. D12.776w.543w.484w.500.180w
  6. D12.776w.543w.550w.418.180w
  7. D12.776w.543w.550w.746w.250w
  8. D12.776w.543w.750w.705w.970w.250w

AMA Style

References

  1. National Library of Medicine. CD48 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D000071178. http://id.nlm.nih.gov/mesh/2026/D000071178
  2. CD48 Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/CD48
  3. CD48 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q21130880