Chemicals and Drugs

Bone Morphogenetic Proteins

Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

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Classification

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Synonyms

3 entry terms
  • Bone Morphogenetic Protein
  • Morphogenetic Protein, Bone
  • Morphogenetic Proteins, Bone

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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Indexing Annotation

general; prefer specifics

MeSH Record

History Note

97; was BONE MORPHOGENETIC PROTEIN (NM) 1981-96

MeSH Record

Previous Indexing

  • Proteins (1981-1996)

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AMA Style

References

  1. National Library of Medicine. Bone Morphogenetic Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D019485. http://id.nlm.nih.gov/mesh/2026/D019485
  2. Bone Morphogenetic Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Bone_morphogenetic_protein
  3. Bone Morphogenetic Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q425383