Chemicals and Drugs

Bone Morphogenetic Protein 1

A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Procollagen C-Endopeptidase
  • Procollagen C Endopeptidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009(1978)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.300w.480w.525w.700.049w
  2. D08.811w.277w.656w.675w.374w.525w.700.900.500w
  3. D12.644w.276.954.200w.100w
  4. D12.776w.467.836.049w
  5. D12.776w.467.942.200w.100w
  6. D12.776w.467.948.500w
  7. D23.529.942.200w.100w
  8. D23.529.948.500w

AMA Style

References

  1. National Library of Medicine. Bone Morphogenetic Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D055395. http://id.nlm.nih.gov/mesh/2026/D055395
  2. Bone Morphogenetic Protein 1. In: Wikipedia. https://en.wikipedia.org/wiki/Bone_morphogenetic_protein_1
  3. Bone Morphogenetic Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q426782