Phenomena and Processes

BRCA1 Genes

A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.

MeSH Record

Classification

Broader headings

Related Concepts

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See Also

MeSH Record

Synonyms

3 entry terms
  • BRCA1 Gene
  • Genes, BRCA1
  • Gene, BRCA1

MeSH Record

Aspects Covered

3 allowable subheadings

Indexed with the subheadings drug effects, physiology, radiation effects.

MeSH Record

Indexing Annotation

BRCA stands for "BReast CAncer"

MeSH Record

History Note

97

MeSH Record

Previous Indexing

  • Genes, Suppressor, Tumor (1993-1996)

MeSH Hierarchy

Tree Numbers

  1. G05.360w.340w.024.340w.375.249w.100
  2. G05.360w.340w.024.340w.415.400w.100

AMA Style

References

  1. National Library of Medicine. BRCA1 Genes. Medical Subject Headings (MeSH). 2026. Unique ID D019398. http://id.nlm.nih.gov/mesh/2026/D019398
  2. BRCA1 Genes. In: Wikidata. https://www.wikidata.org/wiki/Q227339