Structured Summary
Abstract
The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
9 entry terms
- Autophagocytosis
- Autophagy, Cellular
- Cellular Autophagy
- ER-Phagy
- Lipophagy
- Nucleophagy
- Reticulophagy
- Ribophagy
- ER Phagy
MeSH Record
Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
MeSH Record
Indexing Annotation
general or unspecified; note specifics; do not confuse with AUTOPHAGIC CELL DEATH, a form of regulated cell death
MeSH Record
History Note
2006(1979)
MeSH Record
Previous Indexing
- Autolysis (1968-1978)
- Lysosomes (1966-1978)
- Phagocytosis (1966-1978)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QU 375
AMA Style
References
- National Library of Medicine. Autophagy. Medical Subject Headings (MeSH). 2026. Unique ID D001343. http://id.nlm.nih.gov/mesh/2026/D001343
- Autophagy. In: Wikipedia. https://en.wikipedia.org/wiki/Autophagy
- Autophagy. In: Wikidata. https://www.wikidata.org/wiki/Q288322