Chemicals and Drugs

Apolipoprotein E3

A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

13 entry terms
  • APOE-epsilon 3
  • APOE-epsilon3
  • Apo E-3
  • Apo E3
  • ApoE3
  • Apolipoprotein E-3
  • Apolipoprotein E-epsilon3
  • Isoapolipoprotein E3
  • APOE epsilon 3
  • APOE epsilon3
  • Apo E 3
  • Apolipoprotein E 3
  • Apolipoprotein E epsilon3

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007 (1981)

MeSH Record

Previous Indexing

  • Apolipoproteins E (1983-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Apolipoprotein E3. Medical Subject Headings (MeSH). 2026. Unique ID D053318. http://id.nlm.nih.gov/mesh/2026/D053318
  2. Apolipoprotein E3. In: Wikidata. https://www.wikidata.org/wiki/Q97120119