Chemicals and Drugs

Antigen T-Cell alpha-beta Receptors

T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.

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Synonyms

26 entry terms
  • Antigen Receptors, T-Cell, alpha-beta
  • Receptors, Antigen, T Cell, alpha beta
  • Receptors, Antigen, T-Cell, alpha-beta
  • T Cell Receptors, alpha beta
  • T-Cell Receptor, alpha-beta
  • T-Cell Receptors, alpha-beta
  • TcR alpha-beta
  • T Cell Receptor, alpha beta
  • TcR alpha beta
  • alpha-beta T-Cell Receptor
  • alpha-beta T-Cell Receptors
  • alpha-beta, TcR
  • Antigen T Cell Receptor, alpha Chain
  • Antigen T Cell Receptor, beta Chain
  • T-Cell Receptor alpha-Chain
  • T-Cell Receptor beta-Chain
  • T-Cell Receptors alpha-Chain
  • T-Cell Receptors beta-Chain
  • T Cell Receptor alpha Chain
  • T Cell Receptor beta Chain
  • T Cell Receptors alpha Chain
  • T Cell Receptors beta Chain
  • alpha-Chain, T-Cell Receptor
  • alpha-Chain, T-Cell Receptors
  • beta-Chain, T-Cell Receptor
  • beta-Chain, T-Cell Receptors

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Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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History Note

92; T-CELL RECEPTORS ALPHA-CHAIN was ANTIGEN T CELL RECEPTOR, ALPHA CHAIN (NM) 1986-91; T-CELL RECEPTORS BETA-CHAIN was ANTIGEN T CELL RECEPTOR, BETA CHAIN (NM) 1986-91

MeSH Record

Previous Indexing

  • Receptors, Antigen, T-Cell (1980-1991)

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References

  1. National Library of Medicine. Antigen T-Cell alpha-beta Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D016693. http://id.nlm.nih.gov/mesh/2026/D016693
  2. Antigen T-Cell alpha-beta Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q21100538