Chemicals and Drugs

Antigen T-Cell Receptor-CD3 Complex

Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (CD3 COMPLEX). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (CD3 COMPLEX). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.

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Classification

Broader headings

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See Also

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Synonyms

6 entry terms
  • Receptor-CD3 Complex, Antigen, T-Cell
  • T-Cell Antigen Receptor-CD3 Complex
  • TCR-CD3 Complex
  • Complex, TCR-CD3
  • T Cell Antigen Receptor CD3 Complex
  • TCR CD3 Complex

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

1993

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1992)
  • Antigens, Differentiation, T-Lymphocyte (1987-1992)
  • Receptors, Antigen, T-Cell (1987-1992)
  • Receptors, Antigen, T-Cell, alpha-beta (1992)
  • Receptors, Antigen, T-Cell, gamma-delta (1992)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.705w.816.824w.800
  2. D23.050w.301.264.894.095w.800
  3. D23.101w.100.894.095w.800

AMA Style

References

  1. National Library of Medicine. Antigen T-Cell Receptor-CD3 Complex. Medical Subject Headings (MeSH). 2026. Unique ID D017260. http://id.nlm.nih.gov/mesh/2026/D017260
  2. Antigen T-Cell Receptor-CD3 Complex. In: Wikidata. https://www.wikidata.org/wiki/Q78193742