Chemicals and Drugs

Angiopoietin-like Proteins

A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.

MeSH Record

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MeSH Record

Synonyms

5 entry terms
  • Angiopoietin-like Protein
  • Angiopoietin-related Protein
  • Angiopoietin like Protein
  • Angiopoietin like Proteins
  • Angiopoietin related Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Angiopoietins (2004-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.100.050w
  2. D12.776w.467.100.050w
  3. D23.529.100.050w

AMA Style

References

  1. National Library of Medicine. Angiopoietin-like Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D000075802. http://id.nlm.nih.gov/mesh/2026/D000075802
  2. Angiopoietin-like Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Angiopoietin-like_proteins
  3. Angiopoietin-like Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q30591455