Chemicals and Drugs

Ampyrone

A metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.

Chemical Identity

Chemical Information

Molecular Formula
C11H13N3O
Molecular Weight
203.24 g/mol
CAS Registry No.
83-07-8
IUPAC Name
4-amino-1,5-dimethyl-2-phenylpyrazol-3-one
InChIKey
RLFWWDJHLFCNIJ-UHFFFAOYSA-N
SMILES
CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N
MeSH Unique ID
D000675
Source
PubChem CID 2151

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 4-Amino-1,5-Dimethyl-2-Phenyl-3H-Pyrazolone
  • 4-Aminoantipyrine
  • 4-Aminophenazone
  • Aminoantipyrine
  • 4 Amino 1,5 Dimethyl 2 Phenyl 3H Pyrazolone
  • 4 Aminoantipyrine
  • 4 Aminophenazone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

an analgesic & non-steroidal anti-inflamm agent

MeSH Record

History Note

91(80); was see under ANTIPYRINE 1980-90

MeSH Record

Previous Indexing

  • Antipyrine (1966-1974) /analogs & derivatives (1975-1979)

MeSH Hierarchy

Tree Number

  1. D03w.383.129w.539.850w.077w.025w

AMA Style

References

  1. National Library of Medicine. Ampyrone. Medical Subject Headings (MeSH). 2026. Unique ID D000675. http://id.nlm.nih.gov/mesh/2026/D000675
  2. Ampyrone. In: Wikipedia. https://en.wikipedia.org/wiki/Ampyrone
  3. Ampyrone. In: Wikidata. https://www.wikidata.org/wiki/Q3599043
  4. Ampyrone. In: PubChem Compound. CID 2151. https://pubchem.ncbi.nlm.nih.gov/compound/2151