Chemicals and Drugs

Aminopyrine

A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of CYTOCHROME P-450 metabolic activity in LIVER FUNCTION TESTS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of AGRANULOCYTOSIS. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of CYTOCHROME P-450 metabolic activity in LIVER FUNCTION TESTS.

Chemical Identity

Chemical Information

Molecular Formula
C13H17N3O
Molecular Weight
231.29 g/mol
CAS Registry No.
58-15-1
IUPAC Name
4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one
InChIKey
RMMXTBMQSGEXHJ-UHFFFAOYSA-N
SMILES
CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)C
MeSH Unique ID
D000632
Source
PubChem CID 6009

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

12 entry terms
  • Amidazophen
  • Amidophen
  • Amidophenazon
  • Amidopyrine
  • Aminofenazone
  • Aminophenazone
  • Dimethyl-N-aminoantipyrine
  • Dimethylaminoantipyrine
  • Dimethylaminophenazone
  • Dipyrine
  • Dimethyl N aminoantipyrine
  • Eufibron

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse entry term DIPYRINE with DIPYRONE

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Aminopyrine. Medical Subject Headings (MeSH). 2026. Unique ID D000632. http://id.nlm.nih.gov/mesh/2026/D000632
  2. Aminopyrine. In: Wikipedia. https://en.wikipedia.org/wiki/Aminophenazone
  3. Aminopyrine. In: Wikidata. https://www.wikidata.org/wiki/Q416503
  4. Aminopyrine. In: PubChem Compound. CID 6009. https://pubchem.ncbi.nlm.nih.gov/compound/6009