Structured Summary
Abstract
A dioxygenase and alkylation repair homolog that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. It can also repair alkylated DNA containing 1-ethenoadenine in vitro. It has highest affinity for double-stranded DNA.
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Classification
Broader headings
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MeSH Record
Synonyms
6 entry terms
- AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase
- Alkylated DNA Repair Protein AlkB Homolog 2
- DNA Oxidative Demethylase ALKBH2
- Oxy DC1 Protein
- AlkB Homolog 2, Alpha Ketoglutarate Dependent Dioxygenase
- Alpha ketoglutarate Dependent Dioxygenase AlkB Homolog 2
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- DNA Repair Enzymes (2004-2016)
- Dioxygenases (2004-2016)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 2. Medical Subject Headings (MeSH). 2026. Unique ID D000071499. http://id.nlm.nih.gov/mesh/2026/D000071499
- Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 2. In: Wikidata. https://www.wikidata.org/wiki/Q21499456