Structured Summary
Abstract
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
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Broader headings
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Drug Class
Pharmacological Action
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Synonyms
18 entry terms
- BMS 188667
- BMS-188667
- BMS-224818
- BMS224818
- Belatacept
- CTLA-4-Ig
- CTLA4-Fc
- CTLA4-Ig
- CTLA4-Ig Immunoconjugate
- Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
- LEA29Y
- Nulojix
- Orencia
- BMS 224818
- BMS188667
- CTLA4 Ig Immunoconjugate
- Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin
- Immunoconjugate, CTLA4-Ig
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2016 (2002)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Abatacept. Medical Subject Headings (MeSH). 2026. Unique ID D000069594. http://id.nlm.nih.gov/mesh/2026/D000069594
- Abatacept. In: Wikipedia. https://en.wikipedia.org/wiki/Abatacept
- Abatacept. In: Wikidata. https://www.wikidata.org/wiki/Q2697833