Structured Summary
Abstract
Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppressed immune activation in immunotherapies.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
33 entry terms
- Immune Checkpoint Blockers
- Immune Checkpoint Inhibitor
- Checkpoint Blockers, Immune
- Checkpoint Inhibitor, Immune
- Checkpoint Inhibitors, Immune
- CTLA-4 Inhibitor
- CTLA-4 Inhibitors
- Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitor
- Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitors
- Immune Checkpoint Blockade
- Immune Checkpoint Inhibition
- PD-1 Inhibitor
- PD-1 Inhibitors
- PD-1-PD-L1 Blockade
- PD-L1 Inhibitor
- PD-L1 Inhibitors
- Programmed Cell Death Protein 1 Inhibitor
- Programmed Cell Death Protein 1 Inhibitors
- Programmed Death-Ligand 1 Inhibitors
- Blockade, PD-1-PD-L1
- CTLA 4 Inhibitor
- CTLA 4 Inhibitors
- Checkpoint Blockade, Immune
- Checkpoint Inhibition, Immune
- Cytotoxic T Lymphocyte Associated Protein 4 Inhibitor
- Cytotoxic T Lymphocyte Associated Protein 4 Inhibitors
- Inhibitor, PD-1
- PD 1 Inhibitor
- PD 1 Inhibitors
- PD 1 PD L1 Blockade
- PD L1 Inhibitor
- PD L1 Inhibitors
- Programmed Death Ligand 1 Inhibitors
MeSH Record
Aspects Covered
22 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2021
MeSH Record
Previous Indexing
- Antineoplastic Agents (2017-2020)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Immune Checkpoint Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D000082082. http://id.nlm.nih.gov/mesh/2026/D000082082
- Immune Checkpoint Inhibitors. In: Wikipedia. https://en.wikipedia.org/wiki/Checkpoint_inhibitor
- Immune Checkpoint Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q39086981