Chemicals and Drugs

Immune Checkpoint Inhibitors

Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppressed immune activation in immunotherapies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppressed immune activation in immunotherapies.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

33 entry terms
  • Immune Checkpoint Blockers
  • Immune Checkpoint Inhibitor
  • Checkpoint Blockers, Immune
  • Checkpoint Inhibitor, Immune
  • Checkpoint Inhibitors, Immune
  • CTLA-4 Inhibitor
  • CTLA-4 Inhibitors
  • Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitor
  • Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitors
  • Immune Checkpoint Blockade
  • Immune Checkpoint Inhibition
  • PD-1 Inhibitor
  • PD-1 Inhibitors
  • PD-1-PD-L1 Blockade
  • PD-L1 Inhibitor
  • PD-L1 Inhibitors
  • Programmed Cell Death Protein 1 Inhibitor
  • Programmed Cell Death Protein 1 Inhibitors
  • Programmed Death-Ligand 1 Inhibitors
  • Blockade, PD-1-PD-L1
  • CTLA 4 Inhibitor
  • CTLA 4 Inhibitors
  • Checkpoint Blockade, Immune
  • Checkpoint Inhibition, Immune
  • Cytotoxic T Lymphocyte Associated Protein 4 Inhibitor
  • Cytotoxic T Lymphocyte Associated Protein 4 Inhibitors
  • Inhibitor, PD-1
  • PD 1 Inhibitor
  • PD 1 Inhibitors
  • PD 1 PD L1 Blockade
  • PD L1 Inhibitor
  • PD L1 Inhibitors
  • Programmed Death Ligand 1 Inhibitors

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2021

MeSH Record

Previous Indexing

  • Antineoplastic Agents (2017-2020)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Immune Checkpoint Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D000082082. http://id.nlm.nih.gov/mesh/2026/D000082082
  2. Immune Checkpoint Inhibitors. In: Wikipedia. https://en.wikipedia.org/wiki/Checkpoint_inhibitor
  3. Immune Checkpoint Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q39086981