Chemicals and Drugs

17 alpha-Hydroxyprogesterone Caproate

Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also used in combination with ESTROGEN in the management of MENSTRUATION DISORDERS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also used in combination with ESTROGEN in the management of MENSTRUATION DISORDERS.

Chemical Identity

Chemical Information

Molecular Formula
C27H40O4
Molecular Weight
428.6 g/mol
CAS Registry No.
630-56-8
IUPAC Name
[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate
InChIKey
DOMWKUIIPQCAJU-LJHIYBGHSA-N
SMILES
CCCCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)C(=O)C
MeSH Unique ID
D000077713
Source
PubChem CID 169870

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • 17 alpha-Oxyprogesterone Capronate
  • 17-Hydroxyprogesterone Capronate
  • 17-alpha-Hydroxy-Progesterone Caproate
  • Hydroxyprogesterone Caproate
  • Hydroxyprogesterone Hexanoate
  • Oxyprogesterone Caproate
  • 17 Hydroxyprogesterone Capronate
  • 17 alpha Hydroxy Progesterone Caproate
  • 17 alpha Hydroxyprogesterone Caproate
  • 17 alpha Oxyprogesterone Capronate
  • Caproate, 17-alpha-Hydroxy-Progesterone
  • Delalutin
  • Makena
  • Neolutin
  • Prolutin Depot
  • Proluton Depot

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1979)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.745w.654w.829w.395w.400w.500w
  2. D06.472w.334.851w.687w.750w.478w.400w.250w

AMA Style

References

  1. National Library of Medicine. 17 alpha-Hydroxyprogesterone Caproate. Medical Subject Headings (MeSH). 2026. Unique ID D000077713. http://id.nlm.nih.gov/mesh/2026/D000077713
  2. 17 alpha-Hydroxyprogesterone Caproate. In: Wikipedia. https://en.wikipedia.org/wiki/Hydroxyprogesterone_caproate
  3. 17 alpha-Hydroxyprogesterone Caproate. In: Wikidata. https://www.wikidata.org/wiki/Q3792032
  4. 17 alpha-Hydroxyprogesterone Caproate. In: PubChem Compound. CID 169870. https://pubchem.ncbi.nlm.nih.gov/compound/169870