Chemicals and Drugs

1,2-Dipalmitoylphosphatidylcholine

Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.

Chemical Identity

Chemical Information

Molecular Formula
C40H80NO8P
Molecular Weight
734.0 g/mol
CAS Registry No.
2644-64-6
IUPAC Name
2,3-di(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
InChIKey
KILNVBDSWZSGLL-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC
MeSH Unique ID
D015060
Source
PubChem CID 6138

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

10 entry terms
  • 1,2-Dihexadecyl-sn-Glycerophosphocholine
  • 1,2-Dipalmitoyl-Glycerophosphocholine
  • Dipalmitoyl Phosphatidylcholine
  • Dipalmitoylglycerophosphocholine
  • Dipalmitoyllecithin
  • Dipalmitoylphosphatidylcholine
  • 1,2 Dihexadecyl sn Glycerophosphocholine
  • 1,2 Dipalmitoyl Glycerophosphocholine
  • 1,2 Dipalmitoylphosphatidylcholine
  • Phosphatidylcholine, Dipalmitoyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

"a major constituent of pulmonary surfactants"; /biosyn /physiol permitted

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Pulmonary Surfactant (1971-1986)
  • Surface-Active Agents (1966-1970)

MeSH Hierarchy

Tree Number

  1. D10w.570w.755w.375.760w.400w.800w.224w

AMA Style

References

  1. National Library of Medicine. 1,2-Dipalmitoylphosphatidylcholine. Medical Subject Headings (MeSH). 2026. Unique ID D015060. http://id.nlm.nih.gov/mesh/2026/D015060
  2. 1,2-Dipalmitoylphosphatidylcholine. In: Wikipedia. https://en.wikipedia.org/wiki/Dipalmitoylphosphatidylcholine
  3. 1,2-Dipalmitoylphosphatidylcholine. In: Wikidata. https://www.wikidata.org/wiki/Q2587934
  4. 1,2-Dipalmitoylphosphatidylcholine. In: PubChem Compound. CID 6138. https://pubchem.ncbi.nlm.nih.gov/compound/6138