Diseases

von Hippel-Lindau Disease

An autosomal dominant disorder caused by mutations in a tumor suppressor gene. This syndrome is characterized by abnormal growth of small blood vessels leading to a host of neoplasms. They include HEMANGIOBLASTOMA in the RETINA; CEREBELLUM; and SPINAL CORD; PHEOCHROMOCYTOMA; pancreatic tumors; and renal cell carcinoma (see CARCINOMA, RENAL CELL). Common clinical signs include HYPERTENSION and neurological dysfunctions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autosomal dominant disorder caused by mutations in a tumor suppressor gene. This syndrome is characterized by abnormal growth of small blood vessels leading to a host of neoplasms. They include HEMANGIOBLASTOMA in the RETINA; CEREBELLUM; and SPINAL CORD; PHEOCHROMOCYTOMA; pancreatic tumors; and renal cell carcinoma (see CARCINOMA, RENAL CELL). Common clinical signs include HYPERTENSION and neurological dysfunctions.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

25 entry terms
  • Angiomatosis Retinae
  • Cerebelloretinal Angiomatosis, Familial
  • Familial Cerebello-Retinal Angiomatosis
  • Hippel-Lindau Disease
  • Lindau Disease
  • Lindau's Disease
  • VHL Syndrome
  • von Hippel-Lindau Syndrome
  • Angiomatoses, Familial Cerebello-Retinal
  • Angiomatoses, Familial Cerebelloretinal
  • Angiomatosis, Familial Cerebello-Retinal
  • Angiomatosis, Familial Cerebelloretinal
  • Cerebello-Retinal Angiomatoses, Familial
  • Cerebello-Retinal Angiomatosis, Familial
  • Cerebelloretinal Angiomatoses, Familial
  • Familial Cerebello Retinal Angiomatosis
  • Familial Cerebello-Retinal Angiomatoses
  • Familial Cerebelloretinal Angiomatoses
  • Familial Cerebelloretinal Angiomatosis
  • Hippel Lindau Disease
  • Lindau's Diseases
  • Lindaus Disease
  • VHL Syndromes
  • von Hippel Lindau Disease
  • von Hippel Lindau Syndrome

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2008 (1975)

MeSH Hierarchy

Tree Numbers

  1. C10w.562w.925w
  2. C14w.907w.077w.925w
  3. C16w.131w.077w.245w.750w
  4. C16w.320w.184w.750w

MeSH Record

NLM Classification

QS 677

AMA Style

References

  1. National Library of Medicine. von Hippel-Lindau Disease. Medical Subject Headings (MeSH). 2026. Unique ID D006623. http://id.nlm.nih.gov/mesh/2026/D006623
  2. von Hippel-Lindau Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Von_Hippel%E2%80%93Lindau_disease
  3. von Hippel-Lindau Disease. In: Wikidata. https://www.wikidata.org/wiki/Q741315