Chemicals and Drugs

tert-Butylhydroperoxide

A direct-acting oxidative stress-inducing agent used to examine the effects of oxidant stress on Ca(2+)-dependent signal transduction in vascular endothelial cells. It is also used as a catalyst in polymerization reactions and to introduce peroxy groups into organic molecules.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A direct-acting oxidative stress-inducing agent used to examine the effects of oxidant stress on Ca(2+)-dependent signal transduction in vascular endothelial cells. It is also used as a catalyst in polymerization reactions and to introduce peroxy groups into organic molecules.

Chemical Identity

Chemical Information

Molecular Formula
C4H10O2
Molecular Weight
90.12 g/mol
CAS Registry No.
75-91-2
IUPAC Name
2-hydroperoxy-2-methylpropane
InChIKey
CIHOLLKRGTVIJN-UHFFFAOYSA-N
SMILES
CC(C)(C)OO
MeSH Unique ID
D020122
Source
PubChem CID 6410

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

11 entry terms
  • t-Butyl Hydroperoxide
  • t-Butylhydroperoxide
  • tert-Butyl Hydroperoxide
  • tertiary-Butylhydroperoxide
  • Hydroperoxide, t-Butyl
  • Hydroperoxide, tert-Butyl
  • t Butyl Hydroperoxide
  • t Butylhydroperoxide
  • tert Butyl Hydroperoxide
  • tert Butylhydroperoxide
  • tertiary Butylhydroperoxide

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1999; use TERT-BUTYLHYDROPEROXIDE (NM) 1980-1998

MeSH Record

Previous Indexing

  • Peroxides (1976-1998)

MeSH Hierarchy

Tree Numbers

  1. D01w.248w.497w.158w.685w.750w.925w
  2. D01w.339w.431w.374w.925w
  3. D01w.650w.550w.750w.900w
  4. D02w.389w.593w.374w.925w

AMA Style

References

  1. National Library of Medicine. tert-Butylhydroperoxide. Medical Subject Headings (MeSH). 2026. Unique ID D020122. http://id.nlm.nih.gov/mesh/2026/D020122
  2. tert-Butylhydroperoxide. In: Wikipedia. https://en.wikipedia.org/wiki/Tert-Butyl_hydroperoxide
  3. tert-Butylhydroperoxide. In: Wikidata. https://www.wikidata.org/wiki/Q286326
  4. tert-Butylhydroperoxide. In: PubChem Compound. CID 6410. https://pubchem.ncbi.nlm.nih.gov/compound/6410