Chemicals and Drugs

rhoC GTP-Binding Protein

A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • ras Homolog Family Member C
  • rhoC GTPase
  • GTP-Binding Protein, rhoC
  • rhoC GTP Binding Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • GTP-Binding Proteins (1991-2017)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.040w.330.300.400.700w.650
  2. D12.776w.157w.325.515.700w.650
  3. D12.776w.476.338.400.700w.650

AMA Style

References

  1. National Library of Medicine. rhoC GTP-Binding Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000075024. http://id.nlm.nih.gov/mesh/2026/D000075024
  2. rhoC GTP-Binding Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21105948