Chemicals and Drugs

rac1 GTP-Binding Protein

A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • TC-25 GTP-Binding Protein
  • rac1 Protein
  • ras-Related C3 Botulinum Toxin Substrate 1
  • GTP-Binding Protein, TC-25
  • GTP-Binding Protein, rac1
  • TC 25 GTP Binding Protein
  • rac1 GTP Binding Protein
  • ras Related C3 Botulinum Toxin Substrate 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000; for RAC1 GENE PRODUCT use RAC GTP-BINDING PROTEINS (NM) 1989-1999

MeSH Record

Previous Indexing

  • G-Proteins (1991-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. rac1 GTP-Binding Protein. Medical Subject Headings (MeSH). 2026. Unique ID D020830. http://id.nlm.nih.gov/mesh/2026/D020830
  2. rac1 GTP-Binding Protein. In: Wikidata. https://www.wikidata.org/wiki/Q4047929