Chemicals and Drugs

p120 GTPase Activating Protein

A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.

MeSH Record

Classification

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MeSH Record

Synonyms

13 entry terms
  • p120 GAP
  • p120-GAP Protein
  • p120rasGAP
  • p125 GAP
  • p125-GAP Protein
  • GAP, p120
  • GAP, p125
  • p120 GAP Protein
  • p125 GAP Protein
  • p100 GAP
  • p100-GAP Protein
  • GAP, p100
  • p100 GAP Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000; for P120-GAP PROTEIN use GTPASE ACTIVATING PROTEINS (NM) 1994-1999; for P100-GAP PROTEIN use GTPASE ACTIVATING PROTEINS (NM) 1995-1999; for P120RASGAP & P125 GAP use GTPASE ACTIVATING PROTEINS (NM) 1996-1999

MeSH Record

Previous Indexing

  • Proteins (1989-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. p120 GTPase Activating Protein. Medical Subject Headings (MeSH). 2026. Unique ID D020729. http://id.nlm.nih.gov/mesh/2026/D020729
  2. p120 GTPase Activating Protein. In: Wikidata. https://www.wikidata.org/wiki/Q58622291