Chemicals and Drugs

mRNA Guanylyltransferases

Enzymes that catalyze the transfer of GMP residue from GTP to 5' end of RNA to form a cap structure identified as G(5')pppN. They can also modify synthetic poly(A) & poly(G) to form m7G(5')pppAn & m7G(5')pppGn.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes that catalyze the transfer of GMP residue from GTP to 5' end of RNA to form a cap structure identified as G(5')pppN. They can also modify synthetic poly(A) & poly(G) to form m7G(5')pppAn & m7G(5')pppGn.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • GTP mRNA Guanylyltransferase
  • RNA Guanylyltransferase
  • m-RNA Guanylyltransferase
  • mRNA 5'-guanylyltransferase
  • mRNA Capping Enzyme
  • mRNA Guanylyltransferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2025 (1976); was mRNA GUANYLYLTRANSFERASE 1976-2025

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.352w.650w.600w.800w
  2. D08.811w.913w.696w.445w.018w

AMA Style

References

  1. National Library of Medicine. mRNA Guanylyltransferases. Medical Subject Headings (MeSH). 2026. Unique ID D000098556. http://id.nlm.nih.gov/mesh/2026/D000098556
  2. mRNA Guanylyltransferases. In: Wikipedia. https://en.wikipedia.org/wiki/MRNA_guanylyltransferase
  3. mRNA Guanylyltransferases. In: Wikidata. https://www.wikidata.org/wiki/Q6717515