Chemicals and Drugs

gamma-Synuclein

A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpressed in a variety of human NEOPLASMS and may be involved in modulating AXON architecture during EMBRYONIC DEVELOPMENT and in the adult. Gamma-Synuclein may also activate SIGNAL TRANSDUCTION PATHWAYS associated with ETS-DOMAIN PROTEIN ELK-1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpressed in a variety of human NEOPLASMS and may be involved in modulating AXON architecture during EMBRYONIC DEVELOPMENT and in the adult. Gamma-Synuclein may also activate SIGNAL TRANSDUCTION PATHWAYS associated with ETS-DOMAIN PROTEIN ELK-1.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Persyn
  • Synoretin
  • gamma Synuclein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1988)

MeSH Hierarchy

Tree Number

  1. D12.776w.631w.860w.750

AMA Style

References

  1. National Library of Medicine. gamma-Synuclein. Medical Subject Headings (MeSH). 2026. Unique ID D051845. http://id.nlm.nih.gov/mesh/2026/D051845
  2. gamma-Synuclein. In: Wikidata. https://www.wikidata.org/wiki/Q24780696