Chemicals and Drugs

gamma-Glutamyltransferase

An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

8 entry terms
  • GGTP
  • Glutamyl Transpeptidase
  • gamma-Glutamyl Transpeptidase
  • gammaglutamyltransferase
  • Transpeptidase, Glutamyl
  • Transpeptidase, gamma-Glutamyl
  • gamma Glutamyl Transpeptidase
  • gamma Glutamyltransferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASES or GLUTAMINYL-PEPTIDE GAMMA-GLUTAMYLTRANSFERASES see TRANSGLUTAMINASES which crosslinks proteins nor with GAMMA-GLUTAMYLCYCLOTRANSFERASE

MeSH Record

History Note

84; was GLUTAMYL TRANSPEPTIDASE 1972-83

MeSH Record

Previous Indexing

  • Acyltransferases (1966-1971)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. gamma-Glutamyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D005723. http://id.nlm.nih.gov/mesh/2026/D005723
  2. gamma-Glutamyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Gamma-glutamyltransferase
  3. gamma-Glutamyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q285870