Chemicals and Drugs

gamma-Globulins

Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • gamma-Globulin
  • gamma Globulin
  • gamma Globulins

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic = AGAMMAGLOBULINEMIA or DYSGAMMAGLOBULINEMIA; index under IMMUNIZATION, PASSIVE for therapy with gamma-globulins in general or unspecified; anti-gamma globulin antibodies = ANTI-ANTIBODIES (IM) + GAMMA-GLOBULINS (IM); gammopathies: coordinate GAMMA-GLOBULINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA, follow text

MeSH Record

History Note

1996 (1963)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.397w
  2. D12.776w.124w.790.651.397w
  3. D12.776w.377w.715.548.397w

AMA Style

References

  1. National Library of Medicine. gamma-Globulins. Medical Subject Headings (MeSH). 2026. Unique ID D005719. http://id.nlm.nih.gov/mesh/2026/D005719
  2. gamma-Globulins. In: Wikipedia. https://en.wikipedia.org/wiki/Gamma_globulin
  3. gamma-Globulins. In: Wikidata. https://www.wikidata.org/wiki/Q5520338