Chemicals and Drugs

beta Subunit Human Chorionic Gonadotropin

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • Chorionic Gonadotropin, beta Chain, Human
  • Chorionic Gonadotropin, beta Polypeptide, Human
  • Chorionic Gonadotropin, beta Subunit, Human
  • HCG, beta Subunit
  • HCG-beta
  • Human Chorionic Gonadotropin, beta Subunit
  • HCG beta

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

96; was HCG-BETA (NM) 1977-95

MeSH Record

Previous Indexing

  • Gonadotropins, Chorionic (1977-1995)
  • Peptide Fragments (1977-1995)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.322w.326w.125
  2. D06.472w.699w.649.367w.125
  3. D12.644w.548w.726.367w.125
  4. D12.776w.780.400w.125
  5. D23.101w.140.325
  6. D23.101w.175

AMA Style

References

  1. National Library of Medicine. beta Subunit Human Chorionic Gonadotropin. Medical Subject Headings (MeSH). 2026. Unique ID D018997. http://id.nlm.nih.gov/mesh/2026/D018997
  2. beta Subunit Human Chorionic Gonadotropin. In: Wikidata. https://www.wikidata.org/wiki/Q21100708