Structured Summary
Abstract
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
12 entry terms
- Importin-beta
- Kap95 protein
- Karyopherin beta
- Karyopherin-beta
- Karyopherin-beta Subunit
- beta Importins
- p92 nuclear protein
- Importin beta
- Importins, beta
- Karyopherin beta Subunit
- Karyopherins, beta
- nuclear protein, p92
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2002; use BETA KARYOPHERINS (NM) 1995-2001; for IMPORTIN-BETA use KARYOPHERINS (NM) 1995-2001
MeSH Record
Previous Indexing
- Nuclear Proteins (1995-2001)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. beta Karyopherins. Medical Subject Headings (MeSH). 2026. Unique ID D028961. http://id.nlm.nih.gov/mesh/2026/D028961
- beta Karyopherins. In: Wikidata. https://www.wikidata.org/wiki/Q76714339