Structured Summary
Abstract
A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.
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Classification
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Synonyms
7 entry terms
- Lymphotoxin alpha1, beta2 Heterotrimer
- Lymphotoxin alpha1beta2
- Lymphotoxin alphabeta
- Lymphotoxin alphabeta Heterotrimer
- Heterotrimer, Lymphotoxin alphabeta
- alpha1beta2, Lymphotoxin
- alphabeta Heterotrimer, Lymphotoxin
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007
MeSH Record
Previous Indexing
- Tumor Necrosis Factors (1974-2006)
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AMA Style
References
- National Library of Medicine. beta2 Heterotrimer Lymphotoxin alpha1. Medical Subject Headings (MeSH). 2026. Unique ID D053361. http://id.nlm.nih.gov/mesh/2026/D053361
- beta2 Heterotrimer Lymphotoxin alpha1. In: Wikidata. https://www.wikidata.org/wiki/Q78188483