Diseases

beta-Thalassemia

A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

45 entry terms
  • Microcytemia, beta Type
  • Thalassemia, beta Type
  • beta Thalassemia
  • Microcytemias, beta Type
  • Thalassemia, beta
  • Thalassemias, beta
  • Thalassemias, beta Type
  • Type Microcytemia, beta
  • Type Microcytemias, beta
  • Type Thalassemia, beta
  • Type Thalassemias, beta
  • beta Thalassemias
  • beta Type Microcytemia
  • beta Type Microcytemias
  • beta Type Thalassemia
  • beta Type Thalassemias
  • Anemia, Cooley's
  • Anemia, Erythroblastic
  • Anemia, Mediterranean
  • Erythroblastic Anemia
  • Hemoglobin F Disease
  • Mediterranean Anemia
  • Thalassemia Intermedia
  • Thalassemia Major
  • Thalassemia Major (beta-Thalassemia Major)
  • Thalassemia Minor
  • Thalassemia Minor (beta-Thalassemia Minor)
  • Anemia, Cooley
  • Anemia, Cooleys
  • Anemias, Erythroblastic
  • Anemias, Mediterranean
  • Cooley's Anemia
  • Disease, Hemoglobin F
  • Intermedia, Thalassemia
  • Intermedias, Thalassemia
  • Major, Thalassemia (beta-Thalassemia Major)
  • Majors, Thalassemia (beta-Thalassemia Major)
  • Mediterranean Anemias
  • Minor, Thalassemia (beta-Thalassemia Minor)
  • Minors, Thalassemia (beta-Thalassemia Minor)
  • Thalassemia Intermedias
  • Thalassemia Major (beta Thalassemia Major)
  • Thalassemia Majors (beta-Thalassemia Major)
  • Thalassemia Minor (beta Thalassemia Minor)
  • Thalassemia Minors (beta-Thalassemia Minor)

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

delta-beta thalassemia = DELTA-THALASSEMIA + BETA-THALASSEMIA

MeSH Record

History Note

93; was see THALASSEMIA 1988-92; ANEMIA, ERYTHROBLASTIC was see THALASSEMIA 1965-92, was heading 1963-64; ANEMIA, COOLEY'S was see THALASSEMIA 1963-92; ANEMIA, MEDITERRANEAN was see THALASSEMIA 1965-92; HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR were see THALASSEMIA 1988-92

MeSH Record

Previous Indexing

  • Thalassemia (1966-1992)

MeSH Hierarchy

Tree Numbers

  1. C15.378w.050w.141w.150w.875w.150w
  2. C15.378w.420w.826w.150w
  3. C16w.320w.070w.875w.150w
  4. C16w.320w.365w.826w.150w

MeSH Record

NLM Classification

WH 170

AMA Style

References

  1. National Library of Medicine. beta-Thalassemia. Medical Subject Headings (MeSH). 2026. Unique ID D017086. http://id.nlm.nih.gov/mesh/2026/D017086
  2. beta-Thalassemia. In: Wikipedia. https://en.wikipedia.org/wiki/Beta_thalassemia
  3. beta-Thalassemia. In: Wikidata. https://www.wikidata.org/wiki/Q3616632