Chemicals and Drugs

bcl-X Protein

A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS and is a regulatory subunit for PROTEIN PHOSPHATASE 1. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS and is a regulatory subunit for PROTEIN PHOSPHATASE 1. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

23 entry terms
  • bcl2-Like 1 Protein
  • bcl2L1 Protein
  • bcl X Protein
  • bcl2 Like 1 Protein
  • bcl-X(L) Protein
  • bcl-X(S) Protein
  • bcl-XL Protein
  • bcl-XS Protein
  • bcl-Xa Protein
  • bcl-Xalpha Protein
  • bcl-Xb Protein
  • bcl-Xbeta Protein
  • bcl-Xlong Protein
  • bcl-Xshort Protein
  • bcl-x(beta) Protein
  • bcl XL Protein
  • bcl XS Protein
  • bcl Xa Protein
  • bcl Xalpha Protein
  • bcl Xb Protein
  • bcl Xbeta Protein
  • bcl Xlong Protein
  • bcl Xshort Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with the closely related BCL2-ASSOCIATED X PROTEIN

MeSH Record

History Note

2006(1993)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. bcl-X Protein. Medical Subject Headings (MeSH). 2026. Unique ID D051020. http://id.nlm.nih.gov/mesh/2026/D051020
  2. bcl-X Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24781455