Chemicals and Drugs

bcl-2-Associated X Protein

A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.

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Classification

Broader headings

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MeSH Record

Synonyms

27 entry terms
  • Bax Apoptosis Regulator Protein
  • Bax Protein
  • bcl2-Associated X Protein
  • Protein, bcl-2-Associated X
  • X Protein, bcl-2-Associated
  • bcl 2 Associated X Protein
  • bcl2 Associated X Protein
  • Bax-alpha Protein
  • Bax-beta Protein
  • Bax-delta Protein
  • Bax-omega Protein
  • Bax-sigma Protein
  • bcl2-Associated X Protein Isoform alpha
  • bcl2-Associated X Protein Isoform beta
  • bcl2-Associated X Protein Isoform delta
  • bcl2-Associated X Protein Isoform omega
  • bcl2-Associated X Protein Isoform sigma
  • Bax alpha Protein
  • Bax beta Protein
  • Bax delta Protein
  • Bax omega Protein
  • Bax sigma Protein
  • bcl2 Associated X Protein Isoform alpha
  • bcl2 Associated X Protein Isoform beta
  • bcl2 Associated X Protein Isoform delta
  • bcl2 Associated X Protein Isoform omega
  • bcl2 Associated X Protein Isoform sigma

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

Don't confuse with the closely related BCL-X PROTEIN

MeSH Record

History Note

2006(1993)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.075.718w.400w
  2. D12.776w.476.075.718w.400w

AMA Style

References

  1. National Library of Medicine. bcl-2-Associated X Protein. Medical Subject Headings (MeSH). 2026. Unique ID D051028. http://id.nlm.nih.gov/mesh/2026/D051028
  2. bcl-2-Associated X Protein. In: Wikipedia. https://en.wikipedia.org/wiki/Apoptosis_regulator_BAX
  3. bcl-2-Associated X Protein. In: Wikidata. https://www.wikidata.org/wiki/Q408476