Structured Summary
Abstract
An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.
Chemical Identity
Chemical Information
- Molecular Formula
- C5H10N2O7P2
- Molecular Weight
- 272.09 g/mol
- CAS Registry No.
- 118072-93-8
- IUPAC Name
- (1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
- InChIKey
- XRASPMIURGNCCH-UHFFFAOYSA-N
- SMILES
- C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O
- MeSH Unique ID
- D000077211
- Source
- PubChem CID 68740
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
11 entry terms
- 2-(Imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosphonic acid
- CGP 42'446
- CGP 42446A
- CGP-42'446
- CGP-42446
- Zoledronate
- Zoledronic Acid Anhydrous
- Zometa
- CGP 42446
- CGP42'446
- CGP42446
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1994)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Zoledronic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D000077211. http://id.nlm.nih.gov/mesh/2026/D000077211
- Zoledronic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Zoledronic_acid
- Zoledronic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q218507
- Zoledronic Acid. In: PubChem Compound. CID 68740. https://pubchem.ncbi.nlm.nih.gov/compound/68740