Phenomena and Processes

X Chromosome Inactivation

A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Lyonization
  • X Inactivation
  • X-Inactivation
  • Chromosome Inactivation, X
  • Inactivation, X
  • Inactivation, X Chromosome
  • X Inactivations
  • Lyon Hypothesis
  • Hypothesis, Lyon

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2006; use DOSAGE COMPENSATION, GENETIC 1982-2005

MeSH Record

Previous Indexing

  • Dosage Compensation, Genetic (1982-2005)
  • X Chromosome (1983-2005)

MeSH Hierarchy

Tree Number

  1. G05.308w.203.249w.970

AMA Style

References

  1. National Library of Medicine. X Chromosome Inactivation. Medical Subject Headings (MeSH). 2026. Unique ID D049951. http://id.nlm.nih.gov/mesh/2026/D049951
  2. X Chromosome Inactivation. In: Wikidata. https://www.wikidata.org/wiki/Q14862225