Structured Summary
Abstract
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
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Classification
Broader headings
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MeSH Record
Synonyms
21 entry terms
- WAS Protein Family
- WASP Protein Family
- Wiskott Aldrich Syndrome Protein Family
- WAS Protein Family, Member 1
- WAS Protein Family, Member 2
- WAS Protein Family, Member 3
- WASF1 Protein
- WASF2 Protein
- WASF3 Protein
- WASP-Family Verprolin Homologous Proteins
- WAVE Proteins
- WAVE1 Protein
- WAVE2 Protein
- WAVE3 Protein
- Wiskott-Aldrich Syndrome Protein Family, Member 1
- Wiskott-Aldrich Syndrome Protein Family, Member 2
- Wiskott-Aldrich Syndrome Protein Family, Member 3
- WASP Family Verprolin Homologous Proteins
- Wiskott Aldrich Syndrome Protein Family, Member 1
- Wiskott Aldrich Syndrome Protein Family, Member 2
- Wiskott Aldrich Syndrome Protein Family, Member 3
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available
MeSH Record
History Note
2006(1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Wiskott-Aldrich Syndrome Protein Family. Medical Subject Headings (MeSH). 2026. Unique ID D051300. http://id.nlm.nih.gov/mesh/2026/D051300
- Wiskott-Aldrich Syndrome Protein Family. In: Wikidata. https://www.wikidata.org/wiki/Q77191649