Diseases

Whipple Disease

A chronic systemic infection by a gram-positive bacterium, Tropheryma whippelii, mainly affecting the SMALL INTESTINE but also the JOINTS; CARDIOVASCULAR SYSTEM; and the CENTRAL NERVOUS SYSTEM. The disease is characterized by fat deposits in the INTESTINAL MUCOSA and LYMPH NODES, malabsorption, DIARRHEA with fatty stools, MALNUTRITION, and ARTHRITIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A chronic systemic infection by a gram-positive bacterium, Tropheryma whippelii, mainly affecting the SMALL INTESTINE but also the JOINTS; CARDIOVASCULAR SYSTEM; and the CENTRAL NERVOUS SYSTEM. The disease is characterized by fat deposits in the INTESTINAL MUCOSA and LYMPH NODES, malabsorption, DIARRHEA with fatty stools, MALNUTRITION, and ARTHRITIS.

MeSH Record

Classification

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MeSH Record

Synonyms

6 entry terms
  • Lipodystrophy, Intestinal
  • Whipple's Disease
  • Disease, Whipple
  • Disease, Whipple's
  • Intestinal Lipodystrophy
  • Whipples Disease

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2004 (1996); use LIPODYSTROPHY, INTESTINAL 1963-1995

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Whipple Disease. Medical Subject Headings (MeSH). 2026. Unique ID D008061. http://id.nlm.nih.gov/mesh/2026/D008061
  2. Whipple Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Whipple%27s_disease
  3. Whipple Disease. In: Wikidata. https://www.wikidata.org/wiki/Q653078