Chemicals and Drugs

WAP Four-Disulfide Core Domain Protein 2

A secreted 25-kDa glycoprotein member of the Whey-acidic-protein (WAP) four-disulfide core (WFDC) domain family with tissue specific expression in the EPIDIDYMIS. It is also expressed in a limited number of other organs which include female reproductive tract, breast tissue, kidney, regions of the respiratory tract and nasopharynx. The protein is a biomarker for epithelial ovarian cancer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A secreted 25-kDa glycoprotein member of the Whey-acidic-protein (WAP) four-disulfide core (WFDC) domain family with tissue specific expression in the EPIDIDYMIS. It is also expressed in a limited number of other organs which include female reproductive tract, breast tissue, kidney, regions of the respiratory tract and nasopharynx. The protein is a biomarker for epithelial ovarian cancer.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • Epididymal Secretory Protein E4
  • WFDC2 Protein
  • Protein, WFDC2
  • WAP Four Disulfide Core Domain Protein 2

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure.

MeSH Record

History Note

2020

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. WAP Four-Disulfide Core Domain Protein 2. Medical Subject Headings (MeSH). 2026. Unique ID D000081102. http://id.nlm.nih.gov/mesh/2026/D000081102
  2. WAP Four-Disulfide Core Domain Protein 2. In: Wikidata. https://www.wikidata.org/wiki/Q21136674