Chemicals and Drugs

Von Hippel-Lindau Tumor Suppressor Protein

A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

2 entry terms
  • VHL Tumor Suppressor Protein
  • Von Hippel Lindau Tumor Suppressor Protein

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1995)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.464w.938.750.875w
  2. D12.776w.624.776.865w

AMA Style

References

  1. National Library of Medicine. Von Hippel-Lindau Tumor Suppressor Protein. Medical Subject Headings (MeSH). 2026. Unique ID D051794. http://id.nlm.nih.gov/mesh/2026/D051794
  2. Von Hippel-Lindau Tumor Suppressor Protein. In: Wikipedia. https://en.wikipedia.org/wiki/Von_Hippel%E2%80%93Lindau_tumor_suppressor
  3. Von Hippel-Lindau Tumor Suppressor Protein. In: Wikidata. https://www.wikidata.org/wiki/Q7941454