Chemicals and Drugs

Vincristine

An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)

Chemical Identity

Chemical Information

Molecular Formula
C46H56N4O10
Molecular Weight
825.0 g/mol
CAS Registry No.
57-22-7
IUPAC Name
methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
InChIKey
OGWKCGZFUXNPDA-XQKSVPLYSA-N
SMILES
CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
MeSH Unique ID
D014750
Source
PubChem CID 5978

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • Leurocristine
  • Citomid
  • Farmistin
  • Oncovin
  • Oncovine
  • Onkocristin
  • Vincasar
  • Vincasar PFS
  • Vincristin Bristol
  • Vincristin medac
  • Vincristine Sulfate
  • Vincrisul
  • Vintec
  • cellcristin
  • PFS, Vincasar
  • Sulfate, Vincristine

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(63)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.436w.681.827w.817w
  2. D03w.633.100.473.402w.681.827w.817w
  3. D03w.633.100.496.500.500w.681.827w.817w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Vincristine. Medical Subject Headings (MeSH). 2026. Unique ID D014750. http://id.nlm.nih.gov/mesh/2026/D014750
  2. Vincristine. In: Wikipedia. https://en.wikipedia.org/wiki/Vincristine
  3. Vincristine. In: Wikidata. https://www.wikidata.org/wiki/Q408977
  4. Vincristine. In: PubChem Compound. CID 5978. https://pubchem.ncbi.nlm.nih.gov/compound/5978