Structured Summary
Abstract
A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H26N2O3
- Molecular Weight
- 354.4 g/mol
- CAS Registry No.
- 1617-90-9
- IUPAC Name
- methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
- InChIKey
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N
- SMILES
- CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O
- MeSH Unique ID
- D014749
- Source
- PubChem CID 15376
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- Cerebroxine
- Devincan
- Pervincamine
- Vincapront
- Vincimax
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
/biosyn permitted if by plant
MeSH Record
History Note
91(79); was see under VINCA ALKALOIDS 1979-90
MeSH Record
Previous Indexing
- Alkaloids (1966-1972)
- Vinca Alkaloids (1973-1978)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Vincamine. Medical Subject Headings (MeSH). 2026. Unique ID D014749. http://id.nlm.nih.gov/mesh/2026/D014749
- Vincamine. In: Wikipedia. https://en.wikipedia.org/wiki/Vincamine
- Vincamine. In: Wikidata. https://www.wikidata.org/wiki/Q416225
- Vincamine. In: PubChem Compound. CID 15376. https://pubchem.ncbi.nlm.nih.gov/compound/15376