Structured Summary
Abstract
A pyrrolidine-carbonitrile derivative and potent inhibitor of DIPEPTIDYL PEPTIDASE 4 that is used in the treatment of TYPE 2 DIABETES MELLITUS.
Chemical Identity
Chemical Information
- Molecular Formula
- C17H25N3O2
- Molecular Weight
- 303.4 g/mol
- CAS Registry No.
- 274901-16-5
- IUPAC Name
- (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile
- InChIKey
- SYOKIDBDQMKNDQ-XWTIBIIYSA-N
- SMILES
- C1C[C@H](N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N
- MeSH Unique ID
- D000077597
- Source
- PubChem CID 6918537
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- (2S)-(((3-Hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile
- Galvus
- NVP-LAF237
- NVP LAF237
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (2005)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Vildagliptin. Medical Subject Headings (MeSH). 2026. Unique ID D000077597. http://id.nlm.nih.gov/mesh/2026/D000077597
- Vildagliptin. In: Wikipedia. https://en.wikipedia.org/wiki/Vildagliptin
- Vildagliptin. In: Wikidata. https://www.wikidata.org/wiki/Q421042
- Vildagliptin. In: PubChem Compound. CID 6918537. https://pubchem.ncbi.nlm.nih.gov/compound/6918537