Structured Summary
Abstract
A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H13N5O4
- Molecular Weight
- 267.24 g/mol
- CAS Registry No.
- 5536-17-4
- IUPAC Name
- (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- InChIKey
- OIRDTQYFTABQOQ-UHTZMRCNSA-N
- SMILES
- C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N
- MeSH Unique ID
- D014740
- Source
- PubChem CID 21704
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
19 entry terms
- 9-beta-Arabinofuranosyladenine
- 9-beta-D-Arabinofuranosyladenine
- Adenine Arabinoside
- Ara A
- Ara-A
- Arabinofuranosyladenine
- Arabinosyladenine
- alpha-Ara A
- alpha-D-Arabinofuranosyladenine
- beta-Ara A
- 9 beta Arabinofuranosyladenine
- 9 beta D Arabinofuranosyladenine
- Arabinoside, Adenine
- alpha Ara A
- alpha D Arabinofuranosyladenine
- beta Ara A
- Vira-A
- Vira A
- ViraA
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an antiviral & antimetabolite
MeSH Record
History Note
79; was ARABINOFURANOSYLADENINE 1977-78, was ARABINOFURANOSYLADENINE see under PURINE NUCLEOSIDES 1975-76
MeSH Record
Previous Indexing
- Adenine (1972-1974)
- Arabinose (1972-1974)
- Nucleosides (1972-1974)
- Purines (1966-1973)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 268.5
AMA Style
References
- National Library of Medicine. Vidarabine. Medical Subject Headings (MeSH). 2026. Unique ID D014740. http://id.nlm.nih.gov/mesh/2026/D014740
- Vidarabine. In: Wikipedia. https://en.wikipedia.org/wiki/Vidarabine
- Vidarabine. In: Wikidata. https://www.wikidata.org/wiki/Q415107
- Vidarabine. In: PubChem Compound. CID 21704. https://pubchem.ncbi.nlm.nih.gov/compound/21704