Chemicals and Drugs

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.

Chemical Identity

Chemical Information

Molecular Formula
C66H75Cl2N9O24
Molecular Weight
1449.2 g/mol
CAS Registry No.
1404-90-6
IUPAC Name
(1S,2R,18R,19R,22S,25R,28R,40S)-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid
InChIKey
MYPYJXKWCTUITO-LYRMYLQWSA-N
SMILES
C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O
MeSH Unique ID
D014640
Source
PubChem CID 14969

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

22 entry terms
  • AB-Vancomycin
  • Diatracin
  • VANCO-cell
  • Vanco Azupharma
  • Vanco-saar
  • Vancocin
  • Vancocin HCl
  • Vancocine
  • Vancomicina Abbott
  • Vancomicina Chiesi
  • Vancomicina Combino Phar
  • Vancomicina Norman
  • Vancomycin Hexal
  • Vancomycin Hydrochloride
  • Vancomycin Lilly
  • Vancomycin Phosphate (1:2)
  • Vancomycin Phosphate (1:2), Decahydrate
  • Vancomycin Sulfate
  • Vancomycin-ratiopharm
  • Vancomycine Dakota
  • Hydrochloride, Vancomycin
  • Sulfate, Vancomycin

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with trade name Vancomin, a vitamin B12 deriv

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.420w.925w
  2. D12.644w.233w.925w

MeSH Record

NLM Classification

QV 350

AMA Style

References

  1. National Library of Medicine. Vancomycin. Medical Subject Headings (MeSH). 2026. Unique ID D014640. http://id.nlm.nih.gov/mesh/2026/D014640
  2. Vancomycin. In: Wikipedia. https://en.wikipedia.org/wiki/Vancomycin
  3. Vancomycin. In: Wikidata. https://www.wikidata.org/wiki/Q424027
  4. Vancomycin. In: PubChem Compound. CID 14969. https://pubchem.ncbi.nlm.nih.gov/compound/14969